由 DH Kaplan 著作 · 1998 · 被引用 2033 次 — This study demonstrates that endogenously produced interferon γ (IFN-γ) forms the basis of a tumor surveillance system that controls development of both ...
由 F Castro 著作 · 2018 · 被引用 1026 次 — Interferon-gamma (IFN-γ) is a pleiotropic molecule with associated antiproliferative, pro-apoptotic and antitumor mechanisms.
由 AM Gocher 著作 · 2022 · 被引用 222 次 — Interferon-γ (IFNγ) is a cytokine that has both protumour and antitumour activities, suggesting that it may serve as a nexus for responsiveness ...
由 H Ding 著作 · 2022 · 被引用 17 次 — IFN-γ plays different roles in both tumor protection and rejection. Patients with IFNγR deficiencies were predisposed to mycobacterial diseases and a higher ...
由 D Jorgovanovic 著作 · 2020 · 被引用 574 次 — IFN-γ interacts with distinct cytokines from the TME to induce cancer growth arrest. Synergistically with TNF, IFN-γ stimulates the senescence ...
由 M Mojic 著作 · 2018 · 被引用 321 次 — Because of its potent anti-tumor activity, IFN-γ has been regarded as a promising cancer immunotherapy agent. Although IFN-γ was rarely tested ...
由 MR Zaidi 著作 · 2019 · 被引用 160 次 — Interferon-gamma (IFNG) has long been implicated as a central orchestrator of antitumor immune responses in the elimination stage of the immunoediting ...
由 M Boulch 著作 · 2023 · 被引用 17 次 — We provide evidence that IFN-γ acted directly on tumor cells to promote apoptosis and that tumor sensitivity to the pro-apoptotic effects of IFN ...